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THE PARK LAB

A Translational Research Lab of Mitochondrial and Mechanobiology at Baylor University

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Research

Our research focuses on molecular mechanisms of vascular and neuronal adaptations to physiological stimuli. Our goal is to provide novel insights for identifying molecular targets in the prevention of cardiovascular disease and neurodegeneration.

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MITOCHONDRIAL

REMODELING

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MECHANO-

TRANSDUCTION

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EV-DERIVED

BIOMARKER

CELL-TO-CELL

COMMUNICATION

News & Events

Latest Publications

Unidirectional flow enhances mitochondrial remodeling and mitochondrial DNA quality control in a p53-TFAM-dependent fashion. 

Flow-induced endothelial mitochondrial remodeling mitigates mtROS and promotes mtDNA integrity in a p53-dependent manner

Redox Biol. 2022 Apr;50:102252. doi: 10.1016/j.redox.2022.102252.

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