Our Innovative transdisciplinary approaches include bioinformatics, molecular physiology, cell biology, genetics, and AI-based machine learning. Our research platforms include in vitro and in vivo models of fluid shear stress, primary cell culture, transgenic mouse, mitochondrial respirometry, site-directed mutagenesis, random DNA mutation capture, flowcytometry-based extracellular vesicle analysis, Digital ELISA, RNAseq, metabolomic profiling and other -omics technologies.